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KMID : 0614620230810060265
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Korean Journal of Gastroenterology
2023 Volume.81 No. 6 p.265 ~ p.269
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Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction
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Gu Hyun-Dam
Cheung Dae-Young
Seo Yeon-Joo
Lee Eun-Jung
Lee Han-Hee
Kim Jin-Il
Park Soo-Heon
Kim Tae-Jung
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Abstract
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This paper reports a 70-year-old female with gastric extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (gastric MALT lymphoma) as a rare case of gastric outlet obstruction. Five years earlier, she initially presented with weight loss and anemia. Esophagogastroduodenoscopy (EGD) revealed multiple gastric and duodenal ulcers with a pyloric deformity, while histology revealed chronic active inflammation and a Helicobacter pylori (H. pylori) infection. Three years earlier, she underwent EGD per the National Cancer Screening Program and was diagnosed with antral and duodenal ulcers. A forceps biopsy specimen from one of the ulcers showed the findings of gastric MALT lymphoma, but she did not visit the hospital for proper management. She visited complaining of a loss of appetite. EGD revealed a gastric outlet obstruction (GOO) caused by antral deformity and pyloric narrowing. A staged workup with CT and PET revealed full-layered, encircling antral wall thickening and several enlarged mesenteric lymph nodes. She was finally diagnosed with a gastric MALT lymphoma at Ann Arbor stage I1E with translocation t(11;18). She was treated with palliative surgery for GOO and systemic chemotherapy with a CHOP regimen. This paper reports a gastric MALT lymphoma that progressed from superficial mucosal lesions to an overt mass with regional lymph node metastasis for five years.
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KEYWORD
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MALT lymphoma, Stomach, Gastric outlet obstruction
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